Differential Diagnosis Considered etiologies included: Primary psychiatric disorder Neuroinflammatory or neurodegenerative disease Endocrine dysfunction Chronic infection (Lyme disease, EBV) Chronic inflammatory response syndrome (CIRS) Environmental toxin exposure (including mycotoxins) The acute onset, lack of psychiatric history, and environmental correlation made a primary psychiatric etiology less likely
According to the American Society of Plastic Surgeons, body contouring procedures rose nearly 6% in 2023, largely attributed to patients seeking solutions after GLP-1-assisted weight loss
[PubMed ID: 33574884]
These include reducing oxidative stress, decreasing neuroinflammation, promoting neuronal survival, and enhancing synaptic plasticity
Amphetamine enters presynaptic neurons by passive diffusion and through plasma membrane monoamine transporters, including the dopamine transporter (DAT) in dopaminergic neurons, the norepinephrine transporter (NET) in adrenergic neurons, and the serotonin transporter (SERT) in serotinergic neurons